USP 175865-59-5 Valganciclovir hydrochloride mo Antiviral
| Huaingoa | Valganciclovir hydrochloride |
| Nga kupu taurite | L-Valine,2-[(2-aMino-1,6-dihydro-6-oxo-9H-purin-9-yl)Methoxy]-3-hydroxypropylester,hydrochloride(1:1);2-[(2- amino-6-oxo-6,9-dihydro-3H-purin-9-yl)methoxy]-3-hydroxypropyl(2S)-2-amino-3-methylbutanoatehydChemicalbookrochloridehydrate;L-Valine,2-[(2-amino- 1,6-dihydro-6-oxo-9H-purin-9-yl)methoxy]-3-hydroxypropylester,monohydrochloridehydrate |
| CAS No. | 175865-59-5 |
| Te ahua | Te paura tioata ma, he ma ranei |
| Tātai rāpoi | C14H22N6O5.HCl |
| Taumaha rāpoi | 390.83 |
| Whakamahinga | Tohu Rongoa, kaupapa Rangahau ranei |
| Te takai | Ka rite ki to tono |
| Rokiroki | Whakaorangia i roto i nga ipu kiki, kare-marama i te waahi makariri |
| Valganciclovir hydrochloride Cas:175865-59-5 | ||
| Nga taonga | Paerewa | Hua |
| Te ahua | Te paura tioata ma, he ma ranei | paura ma |
| Tautuhinga | Te Kohanga Infrared: He rite ki te paerewa tohutoroUltraviolet Absorption: He rite ki te paerewa tohutoroHe otinga i roto i te wai (1 i roto i te 20) ka tutuki nga whakaritenga o nga whakamatautau mo te Chloride | Ka tutuki Ka tutuki
Ka tutuki |
| Te waipiro Isopropyl | ≤1.0% | 0.13% |
| Wai | ≤8.0% | 4.5% |
| Nga konganuku taumaha | ≤20ppm | Ka tutuki |
| Pd | ≤10ppm | ＜10ppm |
| Te toenga i runga i te mura | ≤0.1% | 0.02% |
| Ko nga poke e pa ana | Valganciclovir: /Ganciclovir: ≤1.5%Guanin: ≤1.5% Methoxymethylguanine: ≤0.3% Isovalganciclovir: ≤0.5% Monoacetoxyganciclovir: ≤0.15% Aranga Bis-valine o ganciclovir: ≤0.1% Homologue o valganciclovir: ≤0.25% Imp H: ≤0.1% Imp I: ≤0.1% Ganciclovir monopropionate: ≤0.15% Valganciclovir dimer (stereoisomer A): ≤0.1% Dimer Valganciclovir (stereoisomer B): ≤0.1% Valganciclovir dimer (stereoisomer C): ≤0.1% Kotahi atu te poke i tautuhia: ≤0.1% Katoa etahi atu poke kua tautuhia: ≤0.1% Ganciclovir mono-N-methyl valinate (Whakamātautau 2):≤0.3% He poke takitahi (Whakamatau 1 me 2): ≤0.1 % Tapeke poke kore mohiotia (Whakamātautau 1 me 2): ≤0.25% Katoa nga poke (Whakamātautau 1 me te Whakamātautau 2): ≤3.0 | /0.02%0.01% 0.03% 0.02% ND 0.04% 0.01% 0.01% 0.004% ND ND ND ND Mōrahi 0.04% 0.04%
0.02% Mōrahi 0.02% 0.13% 0.78% |
| Diastereomer ōwehenga | 45:55 ki te 55:45 | 54:46 |
| Enantiomeric parakore o valganciclovir | ≥97.0% | 99.9% |
| Ko te whakamatautau HPLC | 97.0%～102.0% | 98.8% |
| Whakamutunga: he rite ki te USP40. | ||
Nga korero a te Kamupene
√ Ko nga wheako katoa o te paparanga whakahaere i roto i te wheketere me nga kaitoi mohio nga akonga; √ Ko te kounga tonu to maatau whakaaro nui, te punaha QC tino tika; √ 11 tau te mohio ki te kawe i te roopu hoko; √ taiwhanga R&D motuhake; √ E rua nga awheawhe GMP roa kua hainatia; √ He nui nga rawa o nga wheketere mangere mo te kaupapa kua whakaritea; √ He roopu mahi Kairangi me te huarahi rite.
